Instant, 1R (2) Incinerate deals 3 damage to target creature or player. A creature dealt damage this way can't be regenerated this turn. "Who said there are no assurances in life? I assure you this is going to hurt."
Illus. Steve Prescott
7/15/2007: Regeneration abilities that would affect that creature can still be activated; they just won't do anything. The creature can't be regenerated for any reason, even if an effect other than Incinerate would deal lethal damage to it or otherwise destroy it.